Activity of Lactase Enzyme

Know about Lactase Activity:

Bioven Lactase enzyme works by breaking down the beta-glycosidic linkage existing between the molecules into Glucose and galactose. This breakdown is necessary as Glucose is a simpler sugar and can be directly absorbed into the body and thus producing some amount of energy in the form of ATP’s. This process starts with the combination of lactase with another enzyme to form a greater complex of enzyme called lactase-phlorizin hydrolase.

Unit of Lactase Enzyme Activity:

The units of measurement of Lactase activity depends on the type of lactase and the environment in which it is most effective. Commonly FCC ALU (Food Chemical Codex Acid Lactase Unit) and LU (Lactase Units) both the units are used to work in the acidic environment in stomach which acts on Lactose.

“Bioven Lactase Drops” which are manufactured by Biovencer Healthcare are designed in such a way that they can act on lactose in a more neutral pH environment (outside of the stomach/directly in foods) and uses Lactase Units (LU) (more specifically “Neutral Lactase Units”).

How to measure Enzymatic activity of Lactase:

Enzymatic activity is measured with the help of colorimeter by observing the colorimetric reactions. One unit of enzyme activity is defined as the amount of product formed (or substrate used) per unit time and can be given by the following formula:

Genetics behind Lactase Enzyme

The gene responsible for the production of lactase enzyme is LCT gene. The LCT gene is 49.3kb in length and is located on the long arm of chromosome no. 2 at position 21. The LCT gene contains 17 exons. Two variants of LCT gene are associated with Lactase persistence (LCT-13910C>T and LCT-22018G>A). The persons who can not produce Lactase enzyme, the LCT gene is present in mutated form in those persons. Mutations in this gene are associated with congenital lactase deficiency.